The Effect of a Multi-strain Probiotic SLAB51 (Sivomixx800®) on Acclimatization to High Altitude

Active, Not Recruiting Not Applicable NCT06552806

Study Description

The goal of this study is to learn if the probiotic SLAB51 (Sivomixx800®) works to enhance acclimatization to high altitude in humans. The main questions it aims to answer are: Does SLAB51 improve oxygen saturation during high-altitude exposure? Researchers will compare SLAB51 to a placebo (a substance that contains no probiotic) to see if SLAB51 works to enhance high-altitude acclimatization. Participants will: Take SLAB51 or a placebo three times daily during two separate three-night acclimatization periods at high altitude, spaced at least six weeks apart. Complete baseline measurements at sea level. Visit the high-altitude Barcroft Station (3,801 m) at the University of California White Mountain Research Center for physiological measurements and assessments. Undergo assessments including oxygen saturation, ventilation, heart rate, blood pressure, sleep studies, cognitive assessments, exercise capacity, Acute Mountain Sickness scores, and provide blood, fecal, and urine samples for advanced analyses.

Study Details

Registry ID:
NCT06552806
Conditions:
Probiotics
Phase:
Not Applicable
Target Enrollment:
17 participants
Start Date:
Age Range:
18–65 years
Healthy Volunteers:
No

Study Locations (2 sites)

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