Effect of Thiazide, Amiloride and Hypertonic Saline on Sodium- and Water Channel Activity in the Nephron in Healthy Subjects Estimated by Urinary Biomarkers
Completed Not Applicable NCT01635231
Study Description
Urinary biomarkers (u-NKCC2, u-ENaC-gamma and u-AQP2) reflects the activity of the sodium- and water channels in the human kidney. Changes in the sodium-and water channel activity can be induced by blocking the sodium channels with diuretics in healthy subjects
Study Details
- Registry ID:
- NCT01635231
- Conditions:
- Nephropathy
- Phase:
- Not Applicable
- Target Enrollment:
- 24 participants
- Start Date:
- Healthy Volunteers:
- No
Study Locations (1 site)
-
Medical Research
Holstebro, Denmark
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