A Phase 1b Trial of RAY121 in Immunological Diseases

Study Description

A Study Evaluating the Safety and Effectiveness of RAY121 in Patients with Autoimmune Diseases

Study Details

Registry ID:

NCT06371417

Conditions:

Antiphospholipid Syndrome (APS), Bullous Pemphigoid (BP), Behçet's Syndrome (BS), Dermatomyositis (DM), Immune-mediated Necrotizing Myopathy (IMNM), Immune Thrombocytopenia (ITP)

Phase:

Phase 1

Target Enrollment:

144 participants

Start Date:

August 19, 2024

Age Range:

18–85 years

Healthy Volunteers:

No

Study Locations (80 sites)

• The Alfred Hospital
  Melbourne, VictoriaAustralia, Australia
• Hospital Universitario Virgen del Rocio
  Seville, Province Of SevilleSpain, Spain
• Hospital Universitario Virgen del Rocio
  Sevilla, Province Of SevilleSpain, Spain
• Hospital Universitario Reina Sofia
  Cordoba, Province Of CórdobaSpain, Spain
• Hospital Universitari i Politecnic La Fe
  Valencia, Valencian CommunitySpain, Spain
• Hospital Universitario Ramon y Cajal, Servicio de Reumatologia
  Madrid, Community Of MadridSpain, Spain
• Hospital Universitario 12 de October
  Madrid, Community Of MadridSpain, Spain
• Hospital Universitario 12 de October
  Madrid, MadridSpain, Spain
• Hospital Universitario Ramon y Cajal, Servicio de Reumatologia
  Madrid, MadridSpain, Spain
• Hospital Universitari Vall d'Hebron, Internal Medicine Dept.
  Barcelona, Province Of Barcelona And CataloniaSpain, Spain
• Centro Hospitalar de Vila Nova de Gaia/Espinho, E.P.E.
  Vila Nova De Gaia, Porto DistrictPortugal, Portugal
• Centro Clinico Academico Braga
  Braga, Braga DistrictPortugal, Portugal
• Clinica Universidad de Navarra
  Pamplona, Community Of Madrid & NavarreSpain, Spain
• Hopital Lapeyronie,Service d'Immuno Rhumatologie
  Montpellier, OccitanieFrance, France
• Istituto Clinico Humanitas
  Milan, Milan ProvinceItaly, Italy
• IRCCS Istituto Scientifico Romagnolo Per Lo Studio Dei Tumori "Dino Amadori" - IRST
  Meldola, Forlì-Cesena ProvinceItaly, Italy
• Istituto Clinico Humanitas
  Milano, Milan ProvinceItaly, Italy
• Clinical Hospital Center "Sestre Milosrdnice"
  Zagreb, City Of ZagrebCroatia, Croatia
• University hospital centre Zagreb
  Zagreb, City Of ZagrebCroatia, Croatia
• UMHAT Sv Ivan Rilski EAD
  Sofia, Sofia City ProvinceBulgaria, Bulgaria
• "SHATHD" EAD Sofia
  Sofia, Sofia City ProvinceBulgaria, Bulgaria
• AP-HP Hôpital Universitaire Pitié Salpêtrière
  Paris, Île-de-France RegionFrance, France
• AP-HP Hôpital Universitaire Pitié Salpêtrière
  Paris, Île-de-FranceFrance, France
• Universitaetsklinikum Tuebingen
  Tübingen, Baden-WurttembergGermany, Germany
• Universitaetsklinikum Tuebingen
  Tuebingen, Baden-WürttembergGermany, Germany
• UMHAT "Prof. Dr. St. Kirkovich", AD
  Stara Zagora, Stara Zagora ProvinceBulgaria, Bulgaria
• Istanbul University Istanbul Medical Faculty
  Istanbul, Istanbul ProvinceTurkey, Turkey
• Universitaetsklinikum Carl Gustav Carus TU Dresden, Klinik und Poliklinik f. Dermatologie
  Sachsen, BundesländerGermany, Germany
• Szegedi Tudomanyegyetem Szent-Gyorgyi Albert Klinikai Kozpont
  Szeged, Csongrád-Csanád CountyHungary, Hungary
• Universitaetsklinikum Erlangen
  Erlangen, BavariaGermany, Germany
• Semmelweis Egyetem
  BudapestHungary, Hungary
• Centrul Medical Monza SRL
  Bucharest, Bucharest MunicipalityRomania, Romania
• Dr. Abdurrahman Yurtaslan Oncology Teaching and Research Hospital
  Ankara, Ankara ProvinceTurkey, Turkey
• Sanatorium Profesora Arenbergera
  Prague, City Of PragueCzechia, Czechia
• UMC Utrecht
  Utrecht, Utrecht ProvinceNetherlands, Netherlands
• Oncology Institute Prof. Dr. Ion Chiricuta I.O.C.N.
  Cluj-Napoca, Cluj CountyRomania, Romania
• Oncology Institute Prof. Dr. Ion Chiricuta I.O.C.N.
  Cluj-Napoca, ClujRomania, Romania
• University Medical Centre Groningen UMCG
  Groningen, Groningen ProvinceNetherlands, Netherlands
• Immanuel Klinik Rudersdorf
  Rüdersdorf, BrandenburgGermany, Germany
• Universitaetsklinikum Schleswig Holstein - Campus Luebeck, Klinik f Dermatologie, Allergologie u Venerologie
  Luebeck, Schleswig-HolsteinGermany, Germany
• Institute Reumatologii I'm. Eleonory Reicher
  Warszawa, Masovian VoivodeshipPoland, Poland
• Institute Reumatologii I'm. Eleonory Reicher
  Warsaw, Masovian VoivodeshipPoland, Poland
• Sorlandet sykehus Kristiansand
  Kristiansand, Agder CountyNorway, Norway
• Stavanger Universitetssjukehus
  Stavanger, Rogaland CountyNorway, Norway
• Sykehuset Ostfold Fredrikstad
  Fredrikstad, Østfold fylkeNorway, Norway
• Centre de Rhumatologie de l'Est du Quebec
  Rimouski, QuebecCanada, Canada
• DIEX Recherche Sherbrooke Inc.
  Sherbrooke, QuebecCanada, Canada
• University of Pennsylvania, Perelman Center for Advanced Medicine
  Philadelphia, PennsylvaniaUnited States, United States
• Johns Hopkins University
  Baltimore, MarylandUnited States, United States
• The Royal Institution for the Advancement of Learning/McGill University
  Montreal, QuebecCanada, Canada
• Universtity of North Carolina at Chapel Hill
  Chapel Hill, North CarolinaUnited States, United States
• Nerve and Muscle Center of Texas
  Houston, TexasUnited States, United States
• Austin Neuromuscular Center
  Austin, TexasUnited States, United States
• University of California-Irvine
  Orange, CaliforniaUnited States, United States
• National Taiwan University Hospital
  TaipeiTaiwan, Taiwan
• Taichung Veterans General Hospital
  TaipeiTaiwan, Taiwan
• University of Alberta Hospital - Department of Anesthesiology and Pain Medicine
  Edmonton, AlbertaCanada, Canada
• University of Alberta Hospital - Dermatology
  Edmonton, AlbertaCanada, Canada
• Oregon Health & Science University
  Portland, OregonUnited States, United States
• Okayama University Hospital
  OkayamaJapan, Japan
• Hyogo Prefectural Harima-Himeji General Medical Center
  Himeji, HyōgoJapan, Japan
• Kindai University Hospital
  Sakai, OsakaJapan, Japan
• Kindai University Hospital
  Osakasayama, OsakaJapan, Japan
• Kindai University Hospital
  Sayama, OsakaJapan, Japan
• The University of Osaka Hospital
  Suita, OsakaJapan, Japan
• Osaka University Hospital
  Suita, OsakaJapan, Japan
• Hamamatsu University Hospital
  Hamamatsu, ShizuokaJapan, Japan
• Toyama University Hospital
  ToyamaJapan, Japan
• Tokai University Hospital
  Isehara, KanagawaJapan, Japan
• National Center of Neurology and Psychiatry
  KodairaJapan, Japan
• Toho University Omori Medical Center
  Ota-ku, TokyoJapan, Japan
• Institute of Science Tokyo Hospital
  Bunkyō-KuJapan, Japan
• Tohoku University Hospital
  Sendai, MiyagiJapan, Japan
• Tohoku Medical and Pharmaceutical University Hospital
  Sendai, MiyagiJapan, Japan
• Hokkaido University Hospital
  Sapporo, HokkaidoJapan, Japan
• Box Hill Hospital
  Melbourne, VictoriaAustralia, Australia
• The Alfred Hospital
  Melbourne, VictoriaAustralia, Australia
• Royal Prince Alfred Hospital
  Camperdown, New South WalesAustralia, Australia
• Campbelltown Public Hospital
  Sydney, New South WalesAustralia, Australia
• Westmead Hospital
  Sydney, New South WalesAustralia, Australia

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