A Phase 1 study of BMS-986449 with/without nivolumab in advanced solid tumors

Study Description

An early phase clinical trial evaluating the safety and efficacy of an investigational drug (BMS-986449) alone and combined with an approved immunotherapy drug (nivolumab) in patients with advanced solid tumors

Study Details

Registry ID:

NCT05888831

Conditions:

Advanced Solid Tumors

Phase:

Phase 1,Phase 2

Target Enrollment:

100 participants

Start Date:

June 6, 2023

Age Range:

18–999 years

Healthy Volunteers:

No

Study Locations (54 sites)

• Hospital Universitario Virgen de la Victoria
  Málaga, AndalucíaSpain, Spain
• Local Institution - 0015
  Málaga, AndalucíaSpain, Spain
• Hospital Universitario Fundación Jiménez Díaz
  MadridSpain, Spain
• Hospital Universitario HM Sanchinarro
  MadridSpain, Spain
• Local Institution - 0011
  MadridSpain, Spain
• Local Institution - 0014
  MadridSpain, Spain
• Local Institution - 0013
  BadalonaSpain, Spain
• Local Institution - 0013
  Badalona, Barcelona [Barcelona]Spain, Spain
• Institut Català d'Oncologia (ICO) - Badalona
  Badalona, Barcelona [Barcelona]Spain, Spain
• Institut Catalan d Oncologia (ICO) - Badalona
  Badalona, Barcelona [Barcelona]Spain, Spain
• Clinica Universidad de Navarra
  Pamplona, NavarraSpain, Spain
• Local Institution - 0012
  PamplonaSpain, Spain
• Institut Paoli-Calmettes
  Marseille, Provence-Alpes-Côte-d'AzurFrance, France
• Local Institution - 0004
  Marseille, Provence-Alpes-Côte-d'AzurFrance, France
• Fondazione Policlinico Universitario Agostino Gemelli IRCCS - Università Cattolica del Sacro Cuore
  RomaItaly, Italy
• Local Institution - 0025
  RomaItaly, Italy
• Local Institution - 0025
  RomaItaly, Italy
• Institut Paoli-Calmettes
  MarseilleFrance, France
• Azienda Ospedaliero Universitaria Senese
  Siena, ToscanaItaly, Italy
• Local Institution - 0024
  Siena, ToscanaItaly, Italy
• Local Institution - 0003
  BordeauxFrance, France
• Institut Bergonié - Centre Régional de Lutte Contre Le Cancer de Bordeaux et Sud Ouest
  BordeauxFrance, France
• Institut Bergonie Centre Regional de Lutte Contre Le Cancer de Bordeaux Et Sud Ouest
  BordeauxFrance, France
• Centre Leon Berard
  Lyon CEDEX 08, Rhône-AlpesFrance, France
• Local Institution - 0023
  RozzanoItaly, Italy
• Humanitas
  Rozzano, MilanoItaly, Italy
• Local Institution - 0026
  BergamoItaly, Italy
• Local Institution - 0026
  BergamoItaly, Italy
• Azienda Socio Sanitaria Territoriale Papa Giovanni XXIII
  BergamoItaly, Italy
• Local Institution - 0002
  Villejuif, ParisFrance, France
• Gustave Roussy
  VillejuifFrance, France
• Cliniques universitaires Saint-Luc
  Brussels, Bruxelles-Capitale, Région DeBelgium, Belgium
• Local Institution - 0016
  BrusselsBelgium, Belgium
• Local Institution - 0017
  Gent, Oost-VlaanderenBelgium, Belgium
• UZ Gent
  Gent, Oost-VlaanderenBelgium, Belgium
• Local Institution - 0020
  NijmegenNetherlands, Netherlands
• Local Institution - 0030
  AmsterdamNetherlands, Netherlands
• Local Institution - 0030
  AmsterdamNetherlands, Netherlands
• Nederlands Kanker Instituut - Antoni van Leeuwenhoek (NKI-AVL)
  AmsterdamNetherlands, Netherlands
• Nederlands Kanker Instituut Antoni van Leeuwenhoek (NKI AVL)
  Amsterdam, Noord-HollandNetherlands, Netherlands
• Local Institution - 0030
  Amsterdam, Noord-HollandNetherlands, Netherlands
• Local Institution - 0018
  GroningenNetherlands, Netherlands
• University Medical Center Groningen
  GroningenNetherlands, Netherlands
• Local Institution - 0018
  GroningenNetherlands, Netherlands
• Yale University School of Medicine
  New Haven, ConnecticutUnited States, United States
• Yale New Haven Hospital-Smilow Cancer Center
  New Haven, ConnecticutUnited States, United States
• Local Institution - 0007
  New Haven, ConnecticutUnited States, United States
• Northwell Health/ RJ Zuckerberg Cancer Center
  Lake Success, New YorkUnited States, United States
• Local Institution - 0022
  Lake Success, New YorkUnited States, United States
• R.J. Zuckerberg Cancer Center
  Lake Success, New YorkUnited States, United States
• Local Institution - 0010
  Hackensack, New JerseyUnited States, United States
• John Theurer Cancer Center at Hackensack University Medical Center
  Hackensack, New JerseyUnited States, United States
• The Angeles Clinic and Research Institute - West Los Angeles Office
  Los Angeles, CaliforniaUnited States, United States
• Local Institution - 0021
  Los Angeles, CaliforniaUnited States, United States

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