A Phase 1 study of BMS-986470 in healthy volunteers and sickle cell disease patients

Study Description

A study to evaluate the safety and effectiveness of an investigational drug (BMS-986470) in healthy volunteers and patients with sickle cell disease

Study Details

Registry ID:

NCT06481306

Conditions:

Anemia, Sickle Cell, Healthy Volunteers

Phase:

Phase 1,Phase 2

Target Enrollment:

224 participants

Start Date:

July 17, 2024

Age Range:

18–999 years

Healthy Volunteers:

No

Study Locations (51 sites)

• Local Institution - 0015
  MarseilleFrance, France
• Local Institution - 0015
  Marseille, Bouches-du-RhôneFrance, France
• Assistance Publique Hôpitaux de Marseille - Hôpital de la Timone
  MarseilleFrance, France
• Local Institution - 0011
  Milan, LombardyItaly, Italy
• Local Institution - 0009
  VeronaItaly, Italy
• Local Institution - 0037
  PaduaItaly, Italy
• Local Institution - 0061
  CréteilFrance, France
• Hôpital Universitaire Necker Enfants Malades
  ParisFrance, France
• Local Institution - 0023
  ParisFrance, France
• CHU Strasbourg-Hautepierre
  StrasbourgFrance, France
• Institut de cancérologie Strasbourg Europe (ICANS)
  Strasbourg, AlsaceFrance, France
• Local Institution - 0025
  Strasbourg, AlsaceFrance, France
• University Hospitals Sussex NHS Foundation Trust
  East SussexUnited Kingdom, United Kingdom
• Local Institution - 0004
  East SussexUnited Kingdom, United Kingdom
• Local Institution - 0006
  London, London, City OfUnited Kingdom, United Kingdom
• King's College Hospital
  London, London, City ofUnited Kingdom, United Kingdom
• Local Institution - 0044
  London, Greater LondonUnited Kingdom, United Kingdom
• Local Institution - 0047
  LondonUnited Kingdom, United Kingdom
• Local Institution - 0005
  LeedsUnited Kingdom, United Kingdom
• Local Institution - 0016
  Boston, MassachusettsUnited States, United States
• Local Institution - 0024
  Boston, MassachusettsUnited States, United States
• Boston Medical Center
  Boston, MassachusettsUnited States, United States
• Local Institution - 0022
  New Haven, ConnecticutUnited States, United States
• Yale-New Haven Hospital
  New Haven, ConnecticutUnited States, United States
• Local Institution - 0029
  Philadelphia, PennsylvaniaUnited States, United States
• Thomas Jefferson University - Medicine/GI and Hepatology
  Philadelphia, PennsylvaniaUnited States, United States
• Local Institution - 0007
  Philadelphia, PennsylvaniaUnited States, United States
• Local Institution - 0033
  Greenville, North CarolinaUnited States, United States
• Virginia Commonwealth University (VCU) Medical Center
  Richmond, VirginiaUnited States, United States
• Local Institution - 0014
  Richmond, VirginiaUnited States, United States
• Local Institution - 0064
  Baltimore, MarylandUnited States, United States
• Inova Schar Cancer Institute
  Fairfax, VirginiaUnited States, United States
• Local Institution - 0013
  Fairfax, VirginiaUnited States, United States
• Local Institution - 0035
  Tampa, FloridaUnited States, United States
• Local Institution - 0027
  Greenville, South CarolinaUnited States, United States
• Local Institution - 0032
  Pittsburgh, PennsylvaniaUnited States, United States
• Local Institution - 0051
  Toronto, OntarioCanada, Canada
• Winship Cancer Institute of Emory University
  Atlanta, GeorgiaUnited States, United States
• Local Institution - 0017
  Atlanta, GeorgiaUnited States, United States
• Local Institution - 0028
  Cleveland, OhioUnited States, United States
• University of Alabama at Birmingham
  Birmingham, AlabamaUnited States, United States
• Local Institution - 0008
  Birmingham, AlabamaUnited States, United States
• Local Institution - 0034
  Chicago, IllinoisUnited States, United States
• Local Institution - 0030
  St Louis, MissouriUnited States, United States
• ICON
  Lenexa, KansasUnited States, United States
• Local Institution - 0001
  Lenexa, KansasUnited States, United States
• Local Institution - 0021
  La Jolla, CaliforniaUnited States, United States
• University of California San Diego - La Jolla
  La Jolla, CaliforniaUnited States, United States
• Local Institution - 0003
  Oakland, CaliforniaUnited States, United States
• UCSF Benioff Children's Hospital Oakland
  Oakland, CaliforniaUnited States, United States
• Local Institution - 0050
  Vancouver, British ColumbiaCanada, Canada

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