A Phase Ib/III Study of Afuresertib and Fulvestrant in HR+/HER2- Breast Cancer

Study Description

Evaluating the Combination of Afuresertib and Fulvestrant in Patients with Hormone Receptor-Positive, HER2-Negative Breast Cancer

Study Details

Registry ID:

NCT04851613

Conditions:

Breast Cancer

Phase:

Phase 3

Target Enrollment:

256 participants

Start Date:

February 18, 2022

Age Range:

18–999 years

Healthy Volunteers:

No

Study Locations (61 sites)

• University of Vermont
  Burlington, VermontUnited States, United States
• Virginia Cancer Specialists
  Fairfax, VirginiaUnited States, United States
• Piedmont Cancer Institute
  Atlanta, GeorgiaUnited States, United States
• University of Mississippi Medical Center
  Jackson, MississippiUnited States, United States
• University of Iowa
  Iowa City, IowaUnited States, United States
• Sichuan Provincial People's Hospital
  Chengdu, SichuanChina, China
• West China Hospital, Sichuan University
  Chengdu, SichuanChina, China
• Sichuan Cancer Hospital
  Chengdu, SichuanChina, China
• Chongqing University Cancer Hospital
  Chongqing, Chongqing MunicipalityChina, China
• The First Affiliated Hospital of Chongqing Medical University
  Chongqing, Chongqing MunicipalityChina, China
• The First Affiliated Hospital of Guangxi Medical University
  Nanning, GuangxiChina, China
• Guangxi Zhuang Autonomous Region People's Hospital
  Nanning, GuangxiChina, China
• The First People's Hospital of Foshan
  Foshan, GuangdongChina, China
• Sun Yat-sen Memorial Hospital，Sun Yat-sen University
  Guangzhou, GuangdongChina, China
• Sun Yat-sen University Cancer Center
  Guangzhou, GuangdongChina, China
• Zhongshan People's Hospital
  Zhongshan, GuangdongChina, China
• Sun Yat-sen Memorial Hospital of Sun Yat-sen University
  Guangzhou, GuangdongChina, China
• Hunan Cancer Hospital
  Changsha, HunanChina, China
• Hubei Cancer Hospital
  Wuhan, HubeiChina, China
• Wuhan Central Hospital
  Wuhan, HubeiChina, China
• Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology
  Wuhan, HubeiChina, China
• Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology
  Wuhan, HubeiChina, China
• The First Affiliated Hospital of Zhengzhou University
  Zhengzhou, HenanChina, China
• Henan Cancer Hospital
  Zhengzhou, HenanChina, China
• The First Affiliated Hospital of Xi'an Jiaotong University
  Xi’an, ShanxiChina, China
• Anyang cancer hospital
  Anyang, HenanChina, China
• The Fourth Hospital of Hebei Medical University
  Shijiazhuang, HebeiChina, China
• Anhui Provincial Cancer Hospital
  Hefei, AnhuiChina, China
• Affiliated Hospital of Hebei University
  Baoding, HebeiChina, China
• The First Affiliated Hospital of Bengbu Medical College
  Bengbu, AnhuiChina, China
• Fujian Cancer Hospital
  Fuzhou, FujianChina, China
• Shandong Cancer Hospital
  Jinan, ShandongChina, China
• Jiangsu Cancer Hospital
  Nanjing, JiangsuChina, China
• Jiangsu Provincial People's Hospital
  Nanjing, JiangsuChina, China
• Cancer Hospital Chinese Academy of Medical Sciences
  Beijing, BeijingChina, China
• Beijing Cancer Hospital
  Beijing, Beijing MunicipalityChina, China
• Cancer Hospital Chinese Academy of Medical Sciences
  Beijing, Beijing MunicipalityChina, China
• Peking Union Medical College Hospital (PUMCH)
  Beijing, Beijing MunicipalityChina, China
• Providence St. Johns Health Center
  Santa Monica, CaliforniaUnited States, United States
• Tianjin Medical University Cancer Institute & Hospital
  Tianjin, Tianjin MunicipalityChina, China
• Northern Jiangsu People's Hospital
  Yangzhou, JiangsuChina, China
• Tianjin Medical University Cancer Institute & Hospital
  TianjinChina, China
• Zhejiang Cancer Hospital
  Hangzhou, ZhejiangChina, China
• The First Affiliated Hospital of Zhejiang University School of Medicine
  Hangzhou, ZhejiangChina, China
• Sir-run shaw Hospital Zhejiang University of Medicine
  Hangzhou, ZhejiangChina, China
• Sir-run run shaw Hospital Zhejiang University of Medicine
  Hangzhou, ZhejiangChina, China
• The First Affiliated Hospital of Soochow University
  Suzhou, JiangsuChina, China
• Tangshan People's Hospital
  Tangshan, HebeiChina, China
• Taizhou Hospital
  Taizhou, ZhejiangChina, China
• Affiliated Hospital of Nantong University
  Nantong, JiangsuChina, China
• Ningbo Li Huili Hospital
  Ningbo, ZhejiangChina, China
• Ruijin Hospital, Shanghai Jiao Tong University School of Medicine
  Shanghai, Shanghai MunicipalityChina, China
• Zhongshan Hospital, Fudan University
  Shanghai, Shanghai MunicipalityChina, China
• Liaoning Province Cancer Hospital
  Shenyang, LiaoningChina, China
• Shengjing Hospital of China Medical University
  Shenyang, LiaoningChina, China
• The First Hospital of China Medical University
  Shenyang, LiaoningChina, China
• Liaoning Cancer Hospital
  Shenyang, LiaoningChina, China
• The 1st Bethune Hospital of Jilin University
  Changchun, JilinChina, China
• Jilin Provincial Cancer Hospital
  Changchun, JilinChina, China
• The first hospital of Jilin University
  Changchun, JilinChina, China
• Harbin Medical University Cancer Hospital
  Harbin, HeilongjiangChina, China

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