A Two Part First-in-human Phase I Study (With Expanded Cohorts) With the Antibody-drug Conjugate SYD985 to Evaluate the Safety, Pharmacokinetics and Efficacy in Patients With Locally Advanced or Metastatic Solid Tumors
Unknown Phase 1 NCT02277717
Study Description
The purpose of this study is to evaluate the safety of a new medicinal drug SYD985 at different dose levels in patients with cancer, to understand how SYD985 is handled by the body and to evaluate the effect of SYD985 on the cancer.
Study Details
- Registry ID:
- NCT02277717
- Conditions:
- Solid Tumors
- Phase:
- Phase 1
- Target Enrollment:
- 185 participants
- Start Date:
- Healthy Volunteers:
- No
Study Locations (15 sites)
-
START Madrid-CIOCC
Madrid, Spain -
START Madrid-FJD
Madrid, Spain -
Institut Catala d'Oncologia
Barcelona, Spain -
Vall d'Hebron University Hospital
Barcelona, Spain -
Institut Jules Bordet
Brussels, Belgium -
UZ
Gent, Belgium -
Royal Marsden / Institute of Cancer Research
Sutton, United Kingdom -
UZ
Antwerp, Belgium -
Churchill Hospital
Oxford, United Kingdom -
UMC
Rotterdam, Netherlands -
Radboud UMC
Nijmegen, Netherlands -
NKI-AvL
Amsterdam, Netherlands -
The Christie NHS Foundation Trust
Manchester, United Kingdom -
UMC
Groningen, Netherlands -
Beatson Institute for Cancer Research
Glasgow, United Kingdom
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