A Phase 1 Study of BAY 3713372 in MTAP-deleted Solid Tumors

Recruiting Phase 1,Phase 2 NCT06914128

Study Description

A First-in-Human Study to Test the Safety and Effectiveness of BAY 3713372 in Patients with MTAP-deleted Solid Tumors

Study Details

Registry ID:: NCT06914128
Conditions:: MTAP-deleted Solid Tumors
Phase:: Phase 1,Phase 2
Target Enrollment:: 450 participants
Start Date:: March 21, 2025
Age Range:: 18–999 years
Healthy Volunteers:: No

Study Locations (109 sites)

Shizuoka Cancer Center
Sunto, ShizuokaJapan, Japan
Rigshospitalet - Kræftbehandling
Copenhagen OEDenmark, Denmark
Instituto de Investigacion Biomedica de Malaga (IBIMA) - sede Hospital Universitario Virgen de la Victoria (HUVV)
MalagaSpain, Spain
Hospital Universitario Virgen De La Victoria - Oncology
MálagaSpain, Spain
Hospital Universitario Virgen De La Victoria | Oncologia
MálagaSpain, Spain
Hospital Universitario Virgen De La Victoria | Oncologia
Málaga, MálagaSpain, Spain
Instituto de Investigacion Sanitaria (INCLIVA) (Institute of Health Research Hospital Clinic of Valencia)
ValenciaSpain, Spain
Hospital Clinico Universitario De Valencia | Oncologia
ValenciaSpain, Spain
Hospital Clinico Universitario De Valencia | Oncologia
Valencia, ValenciaSpain, Spain
The START Center for Cancer Care - Mardrid-Fundacion Jimenez Diaz (START Madrid-FJD)
MadridSpain, Spain
Hospital Universitario Fundacion Jimenez Diaz | Oncology Service
MadridSpain, Spain
Clinica Universidad De Navarra | Oncologia
MadridSpain, Spain
Hospital Universitario Fundacion Jimenez Diaz | Oncologia
MadridSpain, Spain
Hospital Universitario Fundacion Jimenez Diaz | Oncologia
Madrid, MadridSpain, Spain
NEXT Oncology- Next Madrid
Pozuelo de AlarcónSpain, Spain
NEXT - Hospital Universitario Quironsalud Madrid | Oncologia
Pozuelo de Alarcón, MadridSpain, Spain
Clinica Universidad De Navarra | Pamplona | Oncologia
Pamplona, MadridSpain, Spain
Hospital Hm Nou Delfos - Oncologia
BarcelonaSpain, Spain
Hospital Universitari Vall d'Hebron - Vall d'Hebron Institut d'Oncologia (VHIO)
BarcelonaSpain, Spain
Hospital Universitari Vall d'Hebron- Oncology Service
BarcelonaSpain, Spain
Hospital Universitari Vall D Hebron | Oncologia
BarcelonaSpain, Spain
Hospital Hm Nou Delfos | Oncologia
BarcelonaSpain, Spain
Hospital Hm Nou Delfos | Oncologia
Barcelona, BarcelonaSpain, Spain
Hospital Universitari Vall D Hebron | Oncologia
Barcelona, BarcelonaSpain, Spain
Hospital San Pedro
LogroñoSpain, Spain
Hospital San Pedro | Oncologia
Logroño, La RiojaSpain, Spain
Universidad de Navarra - Clinica Universidad de Navarra (CUN) - Pamplona
PamplonaSpain, Spain
Fondazione IRCCS Istituto Nazionale dei Tumori - S. C. Oncologia Medica 1
MilanItaly, Italy
Humanitas Mirasole S.p.A. - Oncologia Medica ed Ematologia
RozzanoItaly, Italy
Fondazione Policlinico Universitario Agostino Gemelli IRCCS - UOC Fase I
RomaItaly, Italy
I.F.O. Istituti Fisioterapici Ospitalieri - Sperimentazioni cliniche Fase 1 e Medicina di precisione
RomaItaly, Italy
Fondazione IRCCS Istituto Nazionale dei Tumori - S. C. Oncologia Medica 1
MilanoItaly, Italy
Centro di Riferimento Oncologico di Aviano - Oncologia Medica e dei Tumori Immuno-Correlati
AvianoItaly, Italy
Centre Hospitalier Universitaire (CHU) de Liege - Domaine Universitaire du Sart Tilman - Medical Oncology
LiegeBelgium, Belgium
UZ Leuven Gasthuisberg - Pneumology Department
Leuven, Vlaams-BrabantBelgium, Belgium
UZ Leuven Gasthuisberg - Pneumology Department
Leuven, Flemish BrabantBelgium, Belgium
Ghent University Hospital | Drug Research Unit Department
GentBelgium, Belgium
Ghent University Hospital | Drug Research Unit Department
GhentBelgium, Belgium
Ghent University Hospital | Drug Research Unit Department
Ghent, East FlandersBelgium, Belgium
The Royal Marsden NHS Foundation Trust | Sutton - Oak Foundation Drug Development Unit
Sutton, SurreyUnited Kingdom, United Kingdom
Antwerp University Hospital | Oncology Department
AntwerpBelgium, Belgium
Antwerp University Hospital | Oncology Department
Antwerp, AntwerpBelgium, Belgium
The Royal Marsden NHS Foundation Trust
London, Greater LondonUnited Kingdom, United Kingdom
The Royal Marsden NHS Foundation Trust | Sutton - Oak Foundation Drug Development Unit
London, Greater LondonUnited Kingdom, United Kingdom
Masarykova Univerzita - Masarykuv Onkologicky Ustav (MOU) - Klinika Komplexni Onkologicke Pece (KKOP)
BrnoCzechia, Czechia
Masarykova Univerzita - Masarykuv Onkologicky Ustav (MOU) - Klinika Komplexni Onkologicke Pece (KKOP)
Brno, South MoravianCzechia, Czechia
Erasmus Medisch Centrum
RotterdamNetherlands, Netherlands
Erasmus Medisch Centrum
Rotterdam, South HollandNetherlands, Netherlands
Fakultní Nemocnice Olomouc
OlomoucCzechia, Czechia
Fakultní nemocnice Olomouc - Onkologická klinika
OlomoucCzechia, Czechia
Fakultní nemocnice Olomouc - Onkologická klinika
Olomouc, Olomouc RegionCzechia, Czechia
Nederlands Kanker Instituut
AmsterdamNetherlands, Netherlands
Nederlands Kanker Instituut
Amsterdam, North HollandNetherlands, Netherlands
The Christie NHS Foundation Trust
ManchesterUnited Kingdom, United Kingdom
The Christie NHS Foundation Trust | Christie Hospital - Experimental Cancer Medicine Team
ManchesterUnited Kingdom, United Kingdom
Universitair Medisch Centrum Groningen (UMCG) - UMC Groningen Comprehensive Cancer Center
GroningenNetherlands, Netherlands
Universitair Medisch Centrum Groningen (UMCG) - UMC Groningen Comprehensive Cancer Center
Groningen, Provincie GroningenNetherlands, Netherlands
Odense University Hospital - Oncology Department
Odense, Region SyddanmarkDenmark, Denmark
Odense University Hospital | Svendborg Sygehus - Oncology Department
Odense, Region SyddanmarkDenmark, Denmark
Odense University Hospital - Oncology Department
Odense CDenmark, Denmark
Rigshospitalet - Kræftbehandling
CopenhagenDenmark, Denmark
Rigshospitalet - Kræftbehandling
Copenhagen, Capital RegionDenmark, Denmark
Rigshospitalet Copenhagen University Hospital | Oncology Department
Copenhagen, Capital RegionDenmark, Denmark
Sahlgrenska Universitetssjukhuset - Klinisk prövningsenhet Fas I/FIH
GöteborgSweden, Sweden
Sahlgrenska Universitetssjukhuset - Klinisk prövningsenhet Fas I/FIH
GothenburgSweden, Sweden
Sahlgrenska Universitetssjukhuset - Klinisk prövningsenhet Fas I/FIH
Gothenburg, Västra Götaland CountySweden, Sweden
Sahlgrenska Universitetssjukhuset - Sahlgrenska Sjukhuset - Klinisk prövningsenhet Fas I/FIH
Gothenburg, Västra Götaland CountySweden, Sweden
Karolinska Universitetssjukhuset - Fas I-enheten Solna CKC
StockholmSweden, Sweden
Karolinska Universitetssjukhuset - Fas I-enheten Solna CKC
Stockholm, Stockholm CountySweden, Sweden
Karolinska Universitetssjukhuset - Solna - Fas I-enheten Solna CKC
Stockholm, Stockholm CountySweden, Sweden
Massachusetts General Hospital - Neurology
Boston, MassachusettsUnited States, United States
Dana-Farber Cancer Institute - Oncology Department
Boston, MassachusettsUnited States, United States
Memorial Sloan Kettering Cancer Center New York - Main Campus
New York, New YorkUnited States, United States
Icahn School of Medicine at Mount Sinai - Oncology
New York, New YorkUnited States, United States
Florida Cancer Specialists & Research Institute - Lake Nona
Orlando, FloridaUnited States, United States
Sarah Cannon Research Institute at Florida Cancer Specialists- Lake Nona
Orlando, FloridaUnited States, United States
UAB O'Neal Comprehensive Cancer Center - The Kirklin Clinic of UAB Hospital
Birmingham, AlabamaUnited States, United States
SCRI Oncology Partners
Nashville, TennesseeUnited States, United States
START | Midwest
Grand Rapids, MichiganUnited States, United States
Froedtert Hospital - Clinical Cancer Center
Milwaukee, WisconsinUnited States, United States
NEXT Dallas
Irving, TexasUnited States, United States
NEXT Dallas - Oncology Department
Irving, TexasUnited States, United States
START | San Antonio
San Antonio, TexasUnited States, United States
National University Hospital Medical Centre
SingaporeSingapore, Singapore
National Cancer Center Singapore
SingaporeSingapore, Singapore
National Cancer Center Singapore - Oncology Department
SingaporeSingapore, Singapore
Icon Cancer Centre
SingaporeSingapore, Singapore
UCHealth Cancer Center - Anschutz Medical Campus - University of Colorado Cancer Center
Aurora, ColoradoUnited States, United States
Sarah Cannon Research Institute at HealthONE
Denver, ColoradoUnited States, United States
Sarah Cannon - HCA HealthONE Presbyterian St. Luke's - Oncology Department
Denver, ColoradoUnited States, United States
Sarah Cannon Research Institute at HCA HealthONE Presbyterian St. Luke's
Denver, ColoradoUnited States, United States
Tongji Hosp. of Tongji Med Coll, Huazhong Uni of Sci & Tech.
Wuhan, HubeiChina, China
City of Hope - Duarte Cancer Center
Duarte, CaliforniaUnited States, United States
Beijing Cancer Hospital
Beijing, BeijingChina, China
Beijing Cancer Hospital - Oncology Department
Beijing, BeijingChina, China
Beijing Cancer Hospital - Oncology Department
Beijing, Beijing MunicipalityChina, China
UCLA Health Bowyer Oncology Center
Los Angeles, CaliforniaUnited States, United States
Stanford University Medical Center - Neurology
Stanford, CaliforniaUnited States, United States
UCSF Helen Diller Medical Center at Parnassus Heights - Neurology
San Francisco, CaliforniaUnited States, United States
Kindai University Hospital
Sakai, OsakaJapan, Japan
Nagoya University Hospital
Nagoya, Aichi-kenJapan, Japan
National Cancer Center Hospital
Chuo-ku, TokyoJapan, Japan
The Cancer Institute Hospital of JFCR
Koto-ku, TokyoJapan, Japan
National Cancer Center Hospital East
Kashiwa, ChibaJapan, Japan
Northern Hospital
Epping, VictoriaAustralia, Australia
Concord Repatriation General Hospital (CRGH) (Concord Hospital) - Concord Cancer Centre
Concord, New South WalesAustralia, Australia
Chris O'Brien Lifehouse
Camperdown, New South WalesAustralia, Australia
Calvary Mater Hospital Newcastle
Waratah, New South WalesAustralia, Australia
Calvary Mater Hospital Newcastle - Oncology
Waratah, New South WalesAustralia, Australia

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