Preventing Mountain Sickness with Prochlorperazine: A Study

Unknown Phase 2 NCT06450899

Study Description

Are you worried about getting sick while climbing high mountains? A study is examining whether a medication called prochlorperazine can prevent the symptoms of acute mountain sickness, such as headaches and nausea. The medicine is given to some participants, while others receive a harmless placebo, during a hike up to the high altitude of Mount Blue Sky, reaching 4,348 meters. This research involves a carefully managed trip, covering a meal in Golden, Colorado, a climb to the summit, and an overnight stay in summit structures, with the aid of Emergency Physicians to ensure participant safety. During the study, each person’s health is checked using a recognized system (the 2018 LLQ) to see if they develop any signs of acute mountain sickness. The goal is to find out if taking prochlorperazine before and during the ascent can help climbers avoid feeling unwell as they reach greater heights.

Study Details

Registry ID:
NCT06450899
Conditions:
Acute Mountain Sickness
Phase:
Phase 2
Target Enrollment:
57 participants
Start Date:
Age Range:
18–75 years
Healthy Volunteers:
No

Study Locations (1 site)

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