A Phase 2b study of SAB-142 (study medication) in new-onset Type 1 diabetes

Recruiting Phase 2 NCT07187531

Study Description

A study testing whether SAB-142 (study medication) can slow down the progression of newly diagnosed Type 1 diabetes

Study Details

Registry ID:: NCT07187531
Conditions:: Type 1 Diabetes
Phase:: Phase 2
Target Enrollment:: 159 participants
Start Date:: November 25, 2025
Healthy Volunteers:: No

Study Locations (73 sites)

The Children's Hospital of Philadelphia
Philadelphia, PennsylvaniaUnited States, United States
Hospital Universitario Virgen de la Victoria
MálagaSpain, Spain
Hospital Universitario Virgen Macarena
SevilleSpain, Spain
Hospital de Cruces
BarakaldoSpain, Spain
Azienda Ospedaliero Universitaria Maggiore della Carità di Novara
TurinItaly, Italy
IRCCS Ospedale San Raffaele
MilanItaly, Italy
Azienda Ospedaliera Universitaria Integrata Verona-Ospedale della Donna e del Bambino_Borgo Trento
VeronaItaly, Italy
University Children's Hospital Ljubljana (UCHL)
LjubljanaSlovenia, Slovenia
Medizinische Universität Innsbruck
InnsbruckAustria, Austria
Assistance Publique-Hopitaux de Paris (AP-HP) - Hopital Universitaire Robert-Debre
ParisFrance, France
Universite Paris Descartes - Institut Cochin
ParisFrance, France
Medizinische Universitaet Graz - Klinik fuer Innere Medizin
GrazAustria, Austria
Klinikum Augsburg
AugsburgGermany, Germany
Technische Universität Munich
OberschleißheimGermany, Germany
Medizinische Universitaet Wien - Universitaetsklinik fuer Kinder und Jugendheilkunde
ViennaAustria, Austria
Medizinische Universitaet Graz - Universitaetsklinik fuer Kinder und Jugendheilkunde
ViennaAustria, Austria
Groupe sante CHC - Clinique du MontLegia
LiègeBelgium, Belgium
Universitair Ziekenhuis Brussel
JetteBelgium, Belgium
UZ Leuven
LeuvenBelgium, Belgium
Barts Health NHS Trust - The Royal London Hospital
LondonUnited Kingdom, United Kingdom
University College London Hospitals NHS Foundation Trust - University College Hospital
LondonUnited Kingdom, United Kingdom
Noahs Ark Childrens Hospital for Wales
CardiffUnited Kingdom, United Kingdom
Oxford University Hospitals NHS Trust - John Radcliffe Hospital
OxfordUnited Kingdom, United Kingdom
Cambridge University Hospitals NHS Foundation Trust - Addenbrookes Hospital
CambridgeUnited Kingdom, United Kingdom
Nottingham University Hospitals NHS Trust - Queen's Medical Centre (QMC)
NottinghamUnited Kingdom, United Kingdom
Hannoversche Kinderheilanstalt
HanoverGermany, Germany
Alder Hey Children's NHS Foundation Trust
LiverpoolUnited Kingdom, United Kingdom
Uniwersytecki Szital Klniczny w Opolu
OpolePoland, Poland
SZPITAL KLINICZNY im. Karola Jonschera - UNIWERSYTETU MEDYCZNEGO im. Karola Marcinkowskiego
PoznanPoland, Poland
NHS Lothian - Royal Hospital for Sick Children
EdinburghUnited Kingdom, United Kingdom
Warszawski Uniwersytet Medyczny - Klinika Pediatrii
WarsawPoland, Poland
Instytut Diabetologii
WarsawPoland, Poland
MTZ Clinical Research Sp. z o.o.
WarsawPoland, Poland
Steno Diabetes Center
HerlevDenmark, Denmark
Hospital of Lithuanian University of Health Sciences Kauno Klinikos
KaunasLithuania, Lithuania
Turun Yliopistollinen Keskussairaala (TYKS)
TurkuFinland, Finland
Helsingin Yliopistollinen Keskussairaala
HelsinkiFinland, Finland
Harvard Medical School - Joslin Diabetes Center and Joslin Clinical (JDS)
Boston, MassachusettsUnited States, United States
University of Miami - Gables One Tower
Miami, FloridaUnited States, United States
N.C. Children's Hospital - Children's Specialty Clinics - Chapel Hill at Carolina Pointe II
Chapel Hill, North CarolinaUnited States, United States
University of Virginia Health System - Pediatric Diabetes Clinic
Charlottesville, VirginiaUnited States, United States
University of Florida College of Medicine
Gainesville, FloridaUnited States, United States
UPMC Children's Hospital of Pittsburgh
Pittsburgh, PennsylvaniaUnited States, United States
University at Buffalo MD Physicians Group
Buffalo, New YorkUnited States, United States
Asheville Clinical Research
Asheville, North CarolinaUnited States, United States
Children's Healthcare of Atlanta (CHOA) - Center for Advanced Pediatrics
Atlanta, GeorgiaUnited States, United States
IUH - Riley Hospital for Children - Riley Outpatient Center - Pediatric Diabetes & Endocrinology
Indianapolis, IndianaUnited States, United States
Texas Children's Hospital - Clinical Care Center - Pediatric Renal Clinic
Houston, TexasUnited States, United States
Children's Medical Centre Dallas
Dallas, TexasUnited States, United States
Children's Mercy Hospital Kansas - Pediatric Care Clinic
Kansas City, MissouriUnited States, United States
Children's Mercy Hospital Kansas City - Pediatric Care Clinic
Kansas City, MissouriUnited States, United States
Cook Children's Medical Center
Fort Worth, TexasUnited States, United States
San Antonio Clinical Trials
San Antonio, TexasUnited States, United States
Sanford Medical Center Fargo
Fargo, North DakotaUnited States, United States
University of Colorado - Barbara Davis Center for Diabetes
Aurora, ColoradoUnited States, United States
University of New Mexico Hospital
Albuquerque, New MexicoUnited States, United States
Government of Western Australia - Child and Adolescent Health Service - Perth Children's Hospital
NedlandsAustralia, Australia
San Jose Clinical Trials, LLC
San Jose, CaliforniaUnited States, United States
University of California San Francisco Benioff Children's Hospital
San Francisco, CaliforniaUnited States, United States
Mary Bridge Children's Outpatient Center - Tacoma
Tacoma, WashingtonUnited States, United States
Benaroya Research Institute at Virginia Mason
Seattle, WashingtonUnited States, United States
The Royal Melbourne Hospital (RMH)
ParkvilleAustralia, Australia
The Royal Children's Hospital Melbourne
ParkvilleAustralia, Australia
Westmead Hospital
WestmeadAustralia, Australia
Royal North Shore Hospital (RNSH)
St LeonardsAustralia, Australia
Queensland Children's Hospital
BrisbaneAustralia, Australia
Dunedin Hospital
DunedinNew Zealand, New Zealand
New Zealand Clinical Research - Christchurch
ChristchurchNew Zealand, New Zealand
Aotearoa Clinical Trials
Auckland, AucklandNew Zealand, New Zealand
Aotearoa Clinical Trials
AucklandNew Zealand, New Zealand
Waitemata District Health Board- North Shore Hospital
AucklandNew Zealand, New Zealand
Waikato Hospital
HamiltonNew Zealand, New Zealand
Wellington Regional Hospital
WellingtonNew Zealand, New Zealand

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