A Phase 3 study comparing weekly insulin icodec to daily insulin glargine in Type 1 diabetes

Study Description

Weekly vs Daily Long-Acting Insulin Study for Adults with Type 1 Diabetes

Study Details

Registry ID:

NCT07076199

Conditions:

Diabetes Mellitus, Type 1

Phase:

Phase 3

Target Enrollment:

877 participants

Start Date:

August 11, 2025

Healthy Volunteers:

No

Study Locations (185 sites)

• Zentrum für klinische Studien Alexander Segner
  Saint Ingbert-OberwürzbachGermany, Germany
• Die Praxis am Ludwigsplatz
  LudwigshafenGermany, Germany
• S.C. Top Diabet Srl
  Craiova, DoljRomania, Romania
• Spitalul Clinic Judetean De Urgenta Pius Brinzeu Timisoara
  TimisoaraRomania, Romania
• MEDISPEKTRUM s.r.o.
  BratislavaSlovakia, Slovakia
• Diabs&Nutricare Srl
  BucurestiRomania, Romania
• SC Nutrilife SRL
  BucharestRomania, Romania
• Diabs&Nutricare Srl
  BucharestRomania, Romania
• Spitalul Clinic Judetean de Urgenta Sibiu
  SibiuRomania, Romania
• InnoDiab Forschung GmbH
  EssenGermany, Germany
• Diabmed Dr Popescu Alexandrina SRL
  Ploiesti, PrahovaRomania, Romania
• S.C. Dianutrilife Medica S.R.L.
  PloiestiRomania, Romania
• DSP Bochum, Diabetes- und Stoffwechselpraxis
  BochumGermany, Germany
• Praxis für Diabetologie, Angiologie und Innere Medizin Eisenach
  EisenachGermany, Germany
• Centrul Medical de Diagnostic si Tratament Ambulatoriu Neomed
  BrasovRomania, Romania
• MedicalCenter am Clemenshospital - Schwerpunktpraxis für Diabetologie und Ernährungsmedizin
  MünsterGermany, Germany
• Diab - Int, s.r.o.
  BytcaSlovakia, Slovakia
• Spitalul Clinic Judetean De Urgenta Sfantul Apostol Andrei Constanta
  ConstantaRomania, Romania
• Uniklinik TU Dresden Med. Klinik III
  DresdenGermany, Germany
• Uniklinik TU Dresden - Med. Klinik III
  DresdenGermany, Germany
• Institut für Diabetesforschung Osnabrück
  OsnabrückGermany, Germany
• Herz- und Diabeteszentrum NRW - Bad Oeynhausen
  Bad OeynhausenGermany, Germany
• Clinica Korall S.R.L. Satu Mare
  Satu-MareRomania, Romania
• Clinica Korall S.R.L. Satu Mare
  Satu MareRomania, Romania
• HUMAN-CARE s.r.o.
  KosiceSlovakia, Slovakia
• DIOLI s.r.o.
  KosiceSlovakia, Slovakia
• DIADAN, s.r.o. Kosice
  KosiceSlovakia, Slovakia
• HUMAN-CARE, s.r.o.
  KošiceSlovakia, Slovakia
• Formed 2 Sp. z o.o.
  Oswiecim, MalopolskiePoland, Poland
• Formed 2 Sp. z o.o.
  OswiecimPoland, Poland
• Formed 2 Sp. z o.o.
  Oświęcim, Lesser Poland VoivodeshipPoland, Poland
• Beata Mikłaszewicz & Dariusz Dąbrowski "CARDIAMED" s.j.
  Legnica, DolnośląskiePoland, Poland
• Beata Mikłaszewicz & Dariusz Dąbrowski "CARDIAMED" s.j.
  Legnica, Lower Silesian VoivodeshipPoland, Poland
• Beata Miklaszewicz & Dariusz Dabrowski "CARDIAMED" s.j.
  Legnica, Lower Silesian VoivodeshipPoland, Poland
• Zespol Wojewodzkich Przychodni Specjalistycznych W Katowicach SPZOZ
  ZabrzePoland, Poland
• ENDOPRACTICA W.Beker, D.Mielczarek, P.Mielczarek, J.Struzik spółka cywilna
  OpolePoland, Poland
• ENDOPRACTICA W.Beker, D.Mielczarek, P.Mielczarek, J.Struzik spolka cywilna
  OpolePoland, Poland
• CMI Dr. Pletea Noemi SRL
  BacauRomania, Romania
• Minimed S.R.L.
  BacauRomania, Romania
• Med. Cent. Diabet. Endo. Metabol. DIAB-ENDO-MET
  Krakow, MalopolskiePoland, Poland
• Med. Cent. Diabet. Endo. Metabol. DIAB-ENDO-MET
  Krakow, Lesser Poland VoivodeshipPoland, Poland
• Medizinisches Versorgungszentrum Am Bahnhof Spandau GbR
  BerlinGermany, Germany
• Osrodek Badan Klinicznych "METABOLICA" lek. Robert Witek
  Tarnow, MalopolskiePoland, Poland
• Osrodek Badan Klinicznych "METABOLICA" lek. Robert Witek
  Tarnów, Lesser Poland VoivodeshipPoland, Poland
• METABOLICA Sp. z o.o.
  Tarnów, Lesser Poland VoivodeshipPoland, Poland
• Spitalul Judetean De Urgenta Sfantul Ioan Cel Nou Suceava
  SuceavaRomania, Romania
• Diabetes-Zentrum-Wilhelmsburg GbR
  HamburgGermany, Germany
• Diabetes Zentrum Wandsbek Berufsausuebungsgemeinschaft GbR
  HamburgGermany, Germany
• Wendisch/Dahl Hamburg (DZHW)
  HamburgGermany, Germany
• Wendisch - Dahl Hamburg - DZHW
  HamburgGermany, Germany
• Irmed Klimkiewicz Rudziewicz-Kowalska sp. j.
  Piotrkow TrybunalskiPoland, Poland
• Uniwersyteckie Centrum Stomatologii i Medycyny Specjalistycznej Sp. z o.o.
  PoznanPoland, Poland
• Gabinet Lekarski Malgorzata Saryusz-Wolska
  LodzPoland, Poland
• Etg Zamosc Sp. z o.o.
  ZamośćPoland, Poland
• Zanamed Medical Clinic Sp. z o.o.
  LublinPoland, Poland
• Reumed Sp. z o.o.
  LublinPoland, Poland
• Centrum Medyczne Intercor Sp. z o.o.
  BydgoszczPoland, Poland
• PANSTWOWY INSTYTUT MEDYCZNY MSWiA
  WarsawPoland, Poland
• Uniwersyteckie Centrum Kliniczne (UCK)
  GdanskPoland, Poland
• Centro de Endocrinologia Altagracia Alcantara-Gonzalez
  BayamonPuerto Rico, Puerto Rico
• Advanced Clinical Research LLC
  BayamonPuerto Rico, Puerto Rico
• Centro de Endo Altagracia
  BayamónPuerto Rico, Puerto Rico
• Nova Scotia Health Authority
  Halifax, Nova ScotiaCanada, Canada
• Brigham & Women's Hospital
  Boston, MassachusettsUnited States, United States
• Lucas Research Inc.
  Morehead City, North CarolinaUnited States, United States
• Centricity Rsrch MHCity Multi
  Morehead City, North CarolinaUnited States, United States
• Encore Medical Research LLC
  Hollywood, FloridaUnited States, United States
• SRA Trials-Broward
  Pembroke Pines, FloridaUnited States, United States
• Center for Diab,Obes & Metab
  Pembroke Pines, FloridaUnited States, United States
• Metabolic Research Institute Inc
  West Palm Beach, FloridaUnited States, United States
• Latin Clinical Trial Ctr
  Tamarac, FloridaUnited States, United States
• NYC Research, Inc.
  New York, New YorkUnited States, United States
• NYU Langone Health
  New York, New YorkUnited States, United States
• NYU Langone Orthopedic Center
  New York, New YorkUnited States, United States
• Centricity Res New Bern
  New Bern, North CarolinaUnited States, United States
• Thomas Jefferson University Hospital
  Philadelphia, PennsylvaniaUnited States, United States
• Accellacare Wilmington
  Wilmington, North CarolinaUnited States, United States
• Physicians East Endocrinology
  Greenville, North CarolinaUnited States, United States
• Albany Medical College - Endo
  Albany, New YorkUnited States, United States
• AMC Community Endocrinology
  Albany, New YorkUnited States, United States
• Clin des Mal Lipid de Quebec
  Québec, QuebecCanada, Canada
• Clinique des Maladies Lipidiques de Quebec Inc.
  QuébecCanada, Canada
• MedStar Health Research Institute
  Hyattsville, MarylandUnited States, United States
• Accellacare of Raleigh
  Raleigh, North CarolinaUnited States, United States
• West Orange Endocrinology
  Ocoee, FloridaUnited States, United States
• Hanson Clinical Research Center
  Port Charlotte, FloridaUnited States, United States
• MedStar Health Research Institute
  Olney, MarylandUnited States, United States
• McGill University Health Centre
  Montreal, QuebecCanada, Canada
• Centre de Médecine Métabolique de Lanaudière
  Terrebonne, QuebecCanada, Canada
• Centricity Research Mirabel
  Mirabel, QuebecCanada, Canada
• Northeast Research Institute
  Fleming Island, FloridaUnited States, United States
• Suncoast Clinical Research, Inc.
  New Port Richey, FloridaUnited States, United States
• Prisma Health Endo Spc Thy Ctr
  Greenville, South CarolinaUnited States, United States
• University at Buffalo
  Williamsville, New YorkUnited States, United States
• Physicians Research Assoc. LLC
  Lawrenceville, GeorgiaUnited States, United States
• Centricity Research Toronto LMC Multispec
  Toronto, OntarioCanada, Canada
• Centricity Research Etobicoke
  Etobicoke, OntarioCanada, Canada
• Centricity Research Etobicoke Endocrinology
  Etobicoke, OntarioCanada, Canada
• Premier Clinical Trial Research Network (PCTRN)
  Hamilton, OntarioCanada, Canada
• Atlanta Diabetes Associates
  Atlanta, GeorgiaUnited States, United States
• Centricity Research Brampton
  Brampton, OntarioCanada, Canada
• Centricity Research Brampton Endocrinology
  Brampton, OntarioCanada, Canada
• Endocrine Research Solutions, Inc
  Roswell, GeorgiaUnited States, United States
• Centricity Research Columbus
  Columbus, GeorgiaUnited States, United States
• Diab & Endo Assoc of Stark Co
  Canton, OhioUnited States, United States
• Cleveland Clinic_Cleveland
  Cleveland, OhioUnited States, United States
• Western University Centre for Studies in Fam Med
  London, OntarioCanada, Canada
• The Ohio State University Medical Center
  Columbus, OhioUnited States, United States
• University Diabetes & Endocrine Consultants
  Chattanooga, TennesseeUnited States, United States
• Profound Research LLC
  Farmington Hills, MichiganUnited States, United States
• Profound Research LLC
  Clarkston, MichiganUnited States, United States
• Robley Rex VA Medical Center
  Louisville, KentuckyUnited States, United States
• MidState Endocrine Associates
  Nashville, TennesseeUnited States, United States
• Vanderbilt Medical Center_Nashville
  Nashville, TennesseeUnited States, United States
• University Of Chicago
  Chicago, IllinoisUnited States, United States
• Endeavor Health
  Skokie, IllinoisUnited States, United States
• Saint Louis University
  Saint Louis, MissouriUnited States, United States
• Washington University
  Saint Louis, MissouriUnited States, United States
• Saint Louis University
  St Louis, MissouriUnited States, United States
• Washington University
  St Louis, MissouriUnited States, United States
• Prevea Health
  Green Bay, WisconsinUnited States, United States
• The Endocrine Center
  Houston, TexasUnited States, United States
• Amir Ali Hassan, MD, PA
  Houston, TexasUnited States, United States
• Valley Diab. & Endo Comp Ctr
  Weslaco, TexasUnited States, United States
• RGV Endocrine Center
  McAllen, TexasUnited States, United States
• Tekton Research
  McKinney, TexasUnited States, United States
• Epic Medical Research
  DeSoto, TexasUnited States, United States
• Alliance Clinical Network
  Dallas, TexasUnited States, United States
• Velocity Clinical Res-Dallas
  Dallas, TexasUnited States, United States
• Research Institute Of Dallas
  Dallas, TexasUnited States, United States
• Texas Diab Endo ATX N Mopac EXPR
  Austin, TexasUnited States, United States
• Texas Diabetes & Endocrinology
  Austin, TexasUnited States, United States
• Be Well Clinical Studies
  Round Rock, TexasUnited States, United States
• Texas Diabetes & Endocrinology_Round Rock
  Round Rock, TexasUnited States, United States
• Mayo Clinic
  Rochester, MinnesotaUnited States, United States
• Iowa Diabetes Research
  Des Moines, IowaUnited States, United States
• Iowa Diabetes Research
  West Des Moines, IowaUnited States, United States
• N. Texas Diab & Endi - Prime
  Flower Mound, TexasUnited States, United States
• Precision Endo - Revival
  Denton, TexasUnited States, United States
• Diabetes and Thyroid Center of Fort Worth
  Fort Worth, TexasUnited States, United States
• Northeast Clinical Research of San Antonio
  San Antonio, TexasUnited States, United States
• Cotton O’Neil Diabetes & Endocrinology
  Topeka, KansasUnited States, United States
• Cotton O'Neil Diabetes & Endocrinology
  Topeka, KansasUnited States, United States
• International Diabetes Center
  Minneapolis, MinnesotaUnited States, United States
• Alliance for Multispecialty Research
  Norman, OklahomaUnited States, United States
• Lynn Institute of Norman
  Norman, OklahomaUnited States, United States
• Lynn Institute - East OKC
  Oklahoma City, OklahomaUnited States, United States
• University of Nebraska Medical Center
  Omaha, NebraskaUnited States, United States
• QCR Network
  Omaha, NebraskaUnited States, United States
• Amarillo Medical Specialists
  Amarillo, TexasUnited States, United States
• Winnipeg Clinic
  Winnipeg, ManitobaCanada, Canada
• Frontier Medical Ctr
  El Paso, TexasUnited States, United States
• Denver Endocrinology Diabetes and Thyroid Center
  Englewood, ColoradoUnited States, United States
• Albuquerque Clinical Trials Inc.
  Albuquerque, New MexicoUnited States, United States
• Optumcare Colorado Springs
  Golden, ColoradoUnited States, United States
• Rio Clinical Trials
  Ogden, UtahUnited States, United States
• Rocky Mt Clin Res, LLC
  Idaho Falls, IdahoUnited States, United States
• Palm Research Center Inc.
  Las Vegas, NevadaUnited States, United States
• Loma Linda University Faculty Medical Clinics
  Loma Linda, CaliforniaUnited States, United States
• Providence Research
  Fullerton, CaliforniaUnited States, United States
• Providence Medical Foundation
  Fullerton, CaliforniaUnited States, United States
• Pacific Clinical Studies
  Los Alamitos, CaliforniaUnited States, United States
• Pasadena Clinical Trials
  Pasadena, CaliforniaUnited States, United States
• Los Angeles Institute for Metabolic Research
  Los Angeles, CaliforniaUnited States, United States
• Center for Endocrine DM and Metabolic Disorders
  Santa Clarita, CaliforniaUnited States, United States
• Centricity Research Calgary
  Calgary, AlbertaCanada, Canada
• Centricity Research Calgary Endocrinology
  Calgary, AlbertaCanada, Canada
• Clinical Res of Central Ca
  Fresno, CaliforniaUnited States, United States
• John Muir Health
  Concord, CaliforniaUnited States, United States
• Diablo Clinical Research, Inc.
  Walnut Creek, CaliforniaUnited States, United States
• Mills Health Center
  San Mateo, CaliforniaUnited States, United States
• Rainier Clin Res Ctr Inc
  Renton, WashingtonUnited States, United States
• Vancouver General Hospital_Vancouver_0
  Vancouver, British ColumbiaCanada, Canada
• Southern Adelaide Diabetes & Endocrine Services
  Oaklands Park, South AustraliaAustralia, Australia
• Southern Adelaide Diabetes & Endocrine Services
  Oaklands Park, South AustraliaAustralia, Australia
• Townsville University Hospital
  Townsville, QueenslandAustralia, Australia
• Townsville University Hospital
  Townsville, QueenslandAustralia, Australia
• The Royal Melbourne Hospital
  Parkville, VictoriaAustralia, Australia
• St Vincent's Hospital - Melbourne
  Fitzroy, VictoriaAustralia, Australia
• Austin Health, Metabolic Disorders Centre
  Heidelberg Heights, VictoriaAustralia, Australia
• Austin Health, Metabolic Disorders Centre
  Heidelberg Heights, VictoriaAustralia, Australia
• Illawarra Diabetes Service Clinical Trials & Research Unit
  Wollongong, New South WalesAustralia, Australia
• Illawarra Diabetes Service Clinical Trials & Research Unit
  Wollongong, New South WalesAustralia, Australia
• Macquarie University
  Macquarie Park, New South WalesAustralia, Australia
• Macquarie University - Clinical Trials Unit
  Macquarie Park, New South WalesAustralia, Australia

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